He was instructed by his father Armand-Louis; when he was thirty, his father died, and so did his elder brother Pierre-Louis a few months later. Then he succeeded them in their various offices: Saint Gervais, the Sainte-Chapelle, Saint Jean-en-Grève and Les Billettes; he also inherited his father's "quarter" at Notre-Dame Cathedral.
But in 1789, french organists had to do with disturbed time of the Revolution.

And then takes place one of the most amazing scenes of that time: in the nave of Saint Sulpice church, renamed as Victory's Temple, the Board of Directors (the Directoire) tries to charm Bonaparte with a sumptuous banquet; at the Clicquot's monumental organ, Gervais-François is in charge to charm the audience. Three days later, it will be Bonaparte's coup...
Later, Gervais-François will greet the King's Restoration with a piano work, Louis XVIII or The return of happiness in France..

So, like many others, he made his best to survive this period. From the reopening of churches, where they hadn't been destroyed, he resumed his various offices.

His works includes piano works, chamber music, and a few organ works. The Couperin family will extinguish with Gervais-François' only daughter, Céleste, a piano teacher near Paris, whose life will end in destitution in 1860.